sodium valproate; mood stabilaizer; new hopes in addiction medicine
نویسندگان
چکیده
sodium valproate and its derivatives have been widely used for anticonvulsant treatment since the 1970s, but in the past decades, due to its pharmacological and biological features, it has been well used in treatment of various psychiatric disorders, such as mood disorders and substance use disorders. sodium valproate is quickly absorbed in about 1-2 hours after oral taking and maximum plasma concentrations are achieved within 4-5 hours after taking the medicine. its half-life is 16-20 hours which provides possibility of taking it one to two times per day. being well-tolerated with few side effects are the advantages of this medicine that provides possibility to initiate treatment with higher dosage. in such circumstances, clinical respond to the treatment would be also gained faster. i will point out various aspects; such as consumption indications, consumption management, etc… of this medicine, in this article.
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As the brand Epilim, there is a sugar free liquid and oral syrup both containing sodium valproate 200mg in 5ml. It is also available as sodium valproate 100mg crushable tablets, 200mg and 500mg enteric coated tablets and 200mg, 300mg and 500mg modified release tablets. There are also a number of these preparations available as generic formulations both of sodium valproate and valproic acid. It ...
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فصلنامه طب اعتیادجلد ۱، شماره ۱، صفحات ۱۹-۲۰
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